I would guess there's something else going on since his regen messaging system is acting wonky, but you never know. Nonetheless, Diesel Extreme will improve injector deposits if he has any. This maintenance procedure will at least give him a better starting point for diagnosing the problem.
Fuel quality isn't the best in all parts of America, especially if you frequently fill-up in the areas that Ram has identified as troubled areas. The 2020+ owner's manual recommends replacing the fuel filter every 20,000 miles. "If the vehicle is being used in severe operating conditions, or in certain geographical areas of the country (Pennsylvania, New York, Ohio, Maryland, West Virginia, Arkansas, Oklahoma, Kansas, Iowa, Missouri and Nebraska) due to fuel cleanliness issues, it’s recommended to replace the fuel filter every 10,000 miles."
Ram knows there's a problem with high levels of asphaltenes. Some dealers in those states are aware of the issues and will recommend a Mopar fuel additive to help deal with the problem. This will cause injector and DPF problems.